| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (C-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | AP2A2 is a component of the adaptor protein complex 2 (AP-2). AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif. Synonyms: Polyclonal AP2A2 antibody, Anti-AP2A2 antibody, adaptor-related protein complex 2, alpha 2 subunit antibody, ADTAB antibody, CLAPA2 antibody, HIP9 antibody, HYPJ antibody. |
|---|
| Immunogen | AP2 A2 antibody was raised in rabbit using the C terminal of AP2 2 as the immunogen |
|---|
| Other Names | MGC99219|ADTAB|CLAPA2|HIP-9|HIP9|HYPJ|2410074K14Rik|AF006990|AW146353|Adtab|C78001|L25 |
|---|
| Gene, Accession # | Gene ID: 161 |
|---|
| Catalog # | ABIN929411 |
|---|
| Price | |
|---|
| Order / More Info | Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|