| 产品名称 |
Hexokinase, Type IV, Recombinant, Human (Glucokinase, Hexokinase 4, MODY2, HK4, HK IV) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Hexokinase, Type IV, Recombinant, Human (Glucokinase, Hexokinase 4, MODY2, HK4, HK IV) |
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| Description | Purity ~95% by SDS PAGE. Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase4 is found in the liver and pancreatic beta-cells, where it is controlled by insulin (activation) and glucagon (inhibition). In pancreatic beta-cells, type IV enzyme acts as a glucose sensor to modify insulin secretion. Hexokinase4 is commonly called `glucokinase'. Recombinant protein corresponding to human Hexokinase4, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Molecular Weight: 54.3kD (485 amino acids) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLDDRARMEA AKKEKVEQIL AEFQLQEEDL KKSMRRMQKE MDRGLRLETH EEASVKMLPT YVRFTPEGSE VGDFLSLDLG GT |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000153 |
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| Catalog # | H2040-51 |
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| Order / More Info | Hexokinase, Type IV, Recombinant, Human (Glucokinase, Hexokinase 4, MODY2, HK4, HK IV) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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