| 产品详情 |
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| Product Name | CEP-37440 |
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| Description | Purity ≥98% by HPLC. MW: 580.13. CEP-37440 is a potent and selective dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM (ALK cellular IC50 in 75% human plasma). The inhibition leads to disruption of ALK- and FAK-mediated signal transduction pathways and eventually inhibits tumor cell growth in ALK- and FAK-overexpressing tumor cells. It blocks the proliferation of inflammatory and triple-negative breast cancer cell lines but not normal breast epithelial cells. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[5-chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-N-methyl-benzamide; CEP37440 |
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| Gene, Accession, CAS # | CAS: 1391712-60-9 |
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| Catalog # | B2504-5 |
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| Price | |
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| Order / More Info | CEP-37440 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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