| 产品详情 |
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| Product Name | CEP-40783 |
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| Description | Purity ≥98% by HPLC. MW: 588.56. CEP-40783 (RDX-106) is a potent and selective inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. In AXL-transfected 293GT cells, CEP-40783 was 27-fold more active compared to recombinant enzyme with an IC50 value of 0.26 nM. CEP-40783 displays potent AXL and c-Met pharmacodynamic and anti-tumor efficacy in established tumor xenograft models. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RXDX106; CEP40783; N-[4-(6,7-Dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide; RXDX-106 |
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| Gene, Accession, CAS # | CAS: 1437321-24-8 |
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| Catalog # | B2505-1 |
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| Order / More Info | CEP-40783 from BIOVISION, INC. |
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| Product Specific References | n/a |
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