| 产品详情 |
| Edit |   |
|---|
| Product Name | Huwentoxin IV |
|---|
| Description | Selective NaV1.7 channel blocker. Preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). Inhibits the channel by binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration. MW (observed): 4106.79. |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | CAS: 526224-73-7 |
|---|
| Catalog # | 4718/100U |
|---|
| Price | |
|---|
| Order / More Info | Huwentoxin IV from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 30765606 |
|---|
| 产品资料 |
|
|