| 产品详情 |
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| Product Name | KU 55933 |
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| Description | Potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro. Acts as a radio- and chemosensitizer for the treatment of cancer. Purity 98%. MW (observed): 395.49 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one |
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| Gene, Accession, CAS # | CAS: 587871-26-9 |
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| Catalog # | 3544/10 |
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| Price | |
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| Order / More Info | KU 55933 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 15604286, 20538857, 20559319, 20709753, 21160476, 21680529, 21829721, 21930714, 21935375, 22140550, 22173583, 22334513, 22366459, 22377908, 22384045, 22391207, 22426077, 22465953, 22660439, 22854598, 22869596, 23034801, 23045526, 23149945, 23151519, 23253910, 23254285, 23345425, 23345432, 23365423, 23365434, 23836881, 23839822, 23897892, 23963679, 24196438, 24247150, 24370835, 24515437, 24552809, 24572510, 24928515, 25231413, 25299772, 25336634, 25512560, 25560806, 25624349, 25625798, 25645366, 25748550, 25761368, 26057167, 26124108, 26282173, 26439264, 26452218, 26697402, 27057443, 27176072, 27794029 |
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