| 产品详情 |
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| Product Name | UNC0638 |
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| Description | Cell-permeable. UNC0638 is a potent G9a HMTase inhibitor, exhibiting an IC50 value of <15 nM in vitro. UNC0638 also inhibits GLP, a closely-related H3K9 HMTase, with an IC50 value of 19 nM, but is more than 10,000-fold selective against SET7/9 (a H3K4 HMTase), SET8 (a H4K20 HMTase), PRMT3, and SUV39H2. UNC0638 inhibits H3K9 dimethylation in MDA-MB231 cells with an IC50 value of 81 nM and demonstrates favorable separation of functional and toxic effect. MW: 509.72. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-?Cyclohexyl-?6-?methoxy-?N-?[1-?(1-?methylethyl)-?4-?piperidinyl]-?7-?[3-?(1-?pyrrolidinyl)propoxy]-?4-?quinazolinamine |
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| Gene, Accession, CAS # | CAS: 1255580-76-7 |
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| Catalog # | 1933-5 |
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| Order / More Info | UNC0638 from BIOVISION, INC. |
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| Product Specific References | n/a |
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