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Product Name | UNC1999 |
Description | A potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC50 = 2 nM). UNC1999 is >1000-fold selective for other HMTs except EZH1 (22-fold selectivity). It inhibits H3K27 methylation in MCF10A cells with an IC50 of 124 nM as measured by immunofluorescence. MW: 569.74. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-Isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide |
Gene, Accession, CAS # | CAS: 1431612-23-5 |
Catalog # | 2449-25 |
Price | |
Order / More Info | UNC1999 from BIOVISION, INC. |
Product Specific References | n/a |
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