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Product Name | UNC-2025 |
Description | UNC-2025 is a potent inhibitor of the tyrosine kinases Mer and Flt3 (IC50s = 0.74 and 0.80 nM, respectively). It less potently inhibits Axl and Tyro3 (IC50s = 14 and 17 nM, respectively) and a panel of related kinases. UNC2025 blocks colony formation of Mer- and Flt3-dependent tumor cell lines and inhibits Mer phosphorylation in bone marrow leukemia cells in vivo. MW: 476.66. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (1R,4R)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol; MRX-6313 |
Gene, Accession, CAS # | CAS: 1429881-91-3 |
Catalog # | B1262-25 |
Price | |
Order / More Info | UNC-2025 from BIOVISION, INC. |
Product Specific References | n/a |
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