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| Product Name | SIRT6, 1-355aa,Human, His tag, E Coli |
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| Description | MW: 41 kDa (375 aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E Coli and purified by conventional chromatograph |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Sirtuin 6; SIR2L6; Mono-ADP-ribosyltransferase sirtuin-6; SIR2-like protein 6; Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6; SIR2 like protein 6; Sir2 related protein type 6; SIRT 6; Sirtuin (silent mating type information regulation 2 homolog) 6 (S; cerevisiae); Sirtuin 6; Sirtuin type 6; Sirtuin6.] |
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| Gene, Accession, CAS # | SIRT6, Gene ID: 51548, Accession: NP_057623 |
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| Catalog # | MBS203202 |
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| Order / More Info | SIRT6, 1-355aa,Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Michishita E., et al. (2008) Nature. 452 (7186):492-6.; Mostoslavsky R., et al. (2006) Cell. 124 (2):315-29.; |
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