| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Mediator of RNA polymerase II transcription subunit 1 (MED1), partial |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 32.2kDa. Partial: 878-1031aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Activator-recruited cofactor 205KDA component; ARC205; Mediator complex subunit 1; Peroxisome proliferator-activated receptor-binding protein; PBP; PPAR-binding protein; Thyroid hormone receptor-associated protein complex 220KDA component; Trap220; Thyroid receptor-interacting protein 2; TR-interacting protein 2; TRIP-2; Vitamin D receptor-interacting protein complex component DRIP205; p53 regulatory protein RB18A |
|---|
| Gene, Accession, CAS # | MED1, UniProt: Q15648 |
|---|
| Catalog # | RPC23026 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Mediator of RNA polymerase II transcription subunit 1 (MED1), partial from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|