| Edit |   |
| Antigenic Specificity | TCR beta |
| Clone | H57-597 |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | Super Bright 645 conjugate |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry: 0.5 µg/test |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR beta Monoclonal Antibody (H57-597), Super Bright 645, eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodest |
| Immunogen | n/a |
| Other Names | Tib; TCRbeta |
| Gene, Accession # | Entrez: 21577 |
| Catalog # | 64-5961-82 |
| Price | |
| Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |