| 产品详情 |
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| Product Name | Recombinant Aggregatibacter actinomycetemcomitans Leukotoxin (ltxA), partial |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 38.3kDa. Partial: 721-1055aa. N-terminal 6xHis-tagged. Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans). Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts. Shows also beta-hemolytic activity on certain types of growth media. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | AaLta; lktA |
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| Gene, Accession, CAS # | ltxA, UniProt: P16462 |
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| Catalog # | RPC25117 |
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| Order / More Info | Recombinant Aggregatibacter actinomycetemcomitans Leukotoxin (ltxA), partial from BIOMATIK |
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| Product Specific References | n/a |
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