| 产品详情 |
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| Antigenic Specificity | DNA-PKcs Phospho (Thr2609) |
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| Clone | 10B1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-DNA-PKcs Phospho (Thr2609). DNA-protein kinase catalytic subunit (DNA-PKcs) also known as DNA-activated kinase is a nuclear 460-470 kD serine threonine kinase involved in double-stranded DNA break repair, VDJ recombination, and transcriptional modulation. DNA-PKcs must bind DNA ends to become active. DNA-PKcs is modified by phosphorylation and has been shown to interact with Ku70/Ku80, KIP, DNA-ligase IV, and XRCC4 proteins. Phosphorylated DNA-PKcs is upregulated after DNA damaage. The 10B1 monoclonal antibody recognizes phosphorylated human DNA-PKcs (Thr2609) and has been shown to be useful for immunofluorescence staining and Western blotting. |
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| Immunogen | Modified peptide |
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| Other Names | DNA-protein kinase catalytic subunit, DNA-activated protein kinase, DNA-dependent protein kinase |
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| Gene, Accession # | Gene ID: 5591 |
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| Catalog # | 612902 |
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| Price | |
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| Order / More Info | DNA-PKcs Phospho (Thr2609) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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