| 产品详情 |
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| Antigenic Specificity | DNA PKcs/PRKDC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for DNA-dependent protein kinase catalytic subunit(PRKDC) detection. Tested with WB in Human. No cross reactivity with other proteins. PRKDC(Protein Kinase DNA-Activated Catalytic Subunit), also called DNAPK, HYRC1, p350 or DNPK1, is an enzyme that in humans is encoded by the PRKDC gene. DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Satoh et al.(1997) mapped the MCM4 gene to 8q11.2 by FISH. Based on the close proximity of the PRKDC and MCM4 genes, it was assumed that the PRKDC gene also maps to this location. Anderson and Lees-Miller(1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. Daniel et al.(1999) demonstrated that the PRKDC protein participates in retroviral DNA integration, which is catalyzed by the viral protein integrase. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human DNA PKcs(328-346aa AKNAEMHKNKLQYFMEQFY). |
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| Other Names | DNA-dependent protein kinase catalytic subunit;DNA-PK catalytic subunit;DNA-PKcs;2.7.11.1;DNPK1;p460;PRKDC;HYRC, HYRC1; |
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| Gene, Accession # | PRKDC, UniProt: P78527 |
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| Catalog # | PA1970 |
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| Price | |
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| Order / More Info | DNA PKcs/PRKDC Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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