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Product Name | Recombinant Human Leukosialin (SPN), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 39.5kDa. Extracellular Domain: 20-253aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively roved from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Galactoglycoprotein; GALGPLeukocyte sialoglycoprotein; Sialophorin; CD43 |
Gene, Accession, CAS # | SPN, UniProt: P16150 |
Catalog # | RPC22047 |
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Order / More Info | Recombinant Human Leukosialin (SPN), partial from BIOMATIK |
Product Specific References | n/a |
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