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Product Name | Torin 1 |
Description | Potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. Induces autophagy in HeLa cells. Purity 98%. MW (observed): 607.62 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one |
Gene, Accession, CAS # | CAS: 1222998-36-8 |
Catalog # | 4247/10 |
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Order / More Info | Torin 1 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19150980, 22474287, 22576015, 22872865, 23262492, 23274896, 23337583, 23388827, 23401004, 23505321, 23535559, 23547259, 23623748, 23748697, 23918802, 23963679, 24088573, 24092877, 24174532, 24185040, 24206664, 24394643, 24395886, 24448649, 24528777, 24675368, 24834975, 24855105, 24926617, 24945378, 25046112, 25283437, 25288394, 25339774, 25347447, 25378587, 25402767, 25495560, 25556834, 25561175, 25561470, 25582703, 25605458, 25624444, 25653352, 25664849, 25698661, 25714760, 25814944, 25825734, 25843706, 25872869, 25940091, 25945415, 25963655, 26043155, 26119735, 26133373, 26259639, 26302180, 26310906, 26344480, 26355343, 26582390, 26603102, 26689777, 26702100, 26761346, 26801615, 26931735, 26956048, 27040916, 27120463, 27171064, 27227887, 27268300, 27279371, 27325703, 27328819, 27335722, 27341800, 27383256, 27465917, 27731330, 27768726, 27846372, 27894086, 28028537, 28182004, 28306514, 29251248 |
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