| 产品详情 |
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| Antigenic Specificity | CD49b |
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| Clone | P1E6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-CD49b (Integrin α2). CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders. |
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| Immunogen | This monoclonal antibody was generated against human HT1080 fibrosarcoma cells. |
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| Other Names | ITGA2, Integrin alpha-2, collagen receptor, VLA-2 subunit alpha, platelet antigen Br, platelet glycoprotein Ia, platelet glycoprotein GPIa, CD49 antigen-like family member B, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 sub, MMS-488P-100 |
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| Gene, Accession # | Gene ID: 3673 |
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| Catalog # | 910901 |
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| Price | |
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| Order / More Info | CD49b Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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