| 产品详情 |
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| Antigenic Specificity | BRD7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, equine, guinea pig, human, rabbit, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 0.2-2.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BRD7 Polyclonal Antibody. BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase. |
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| Immunogen | n/a |
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| Other Names | Bromodomain containing 7, BP75, CELTIX1, NAG4 |
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| Gene, Accession # | Entrez: 100059012, 100357102, 100726981, 29117, 361374, 478130; Uniprot: Q9NPI1 |
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| Catalog # | PA5-41544 |
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| Price | |
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| Order / More Info | BRD7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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