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| Product Name | GANT 61 |
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| Description | GLI antagonist that inhibits GLI1 and GLI2-induced transcription (IC50 ~ 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo. Inhibits the pluripotency factors Oct4, Sox-2, Nanog and c-Myc in pancreatic cancer stem cells. Purity 98%. MW (observed): 429.61 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
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| Gene, Accession, CAS # | CAS: 500579-04-4 |
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| Catalog # | 3191/10 |
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| Price | |
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| Order / More Info | GANT 61 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21747117, 25544756, 25745035, 26116667, 28965853 |
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| 产品资料 |
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