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Product Name | LFM-A13 |
Description | FM-A13 is a selective inhibitor of Bruton's tyrosine kinase (BTK) - IC50's = 2.5 µM (recombinant BTK) and 17.2 µM (human BTK). It has also been shown to inhibit Polo-like kinase (PLK) (IC50 = 61 µM for human PLK3). It displays no activity (concentrations up to 278 µM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases. MW: 360. Purity ≥98% by TLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2Z) -2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide |
Gene, Accession, CAS # | CAS: 244240-24-2 |
Catalog # | 2414-5 |
Price | |
Order / More Info | LFM-A13 from BIOVISION, INC. |
Product Specific References | n/a |
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