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| Product Name | APEX1, 1-318aa, Human, T7 tag, E Coli |
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| Description | MW: 36.9 kDa (332aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. APEX1, also known as REF1 or APE1 (Apurinic / apyrimidinic endonuclease), is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. APEX1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxid |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [APEX nuclease (multifunctional DNA repair enzyme) 1; APE; APE1; APEN; APX; HAP1; REF-1; REF1] |
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| Gene, Accession, CAS # | APEX1, Gene ID: 328, Accession: AAH19291 |
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| Catalog # | MBS203960 |
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| Order / More Info | APEX1, 1-318aa, Human, T7 tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hinz AK., et al. (2010) J Biol Chem. 285 (37):28683-90.; Wu HH., et al. (2010) Oncogene. 29 (30):4330-40. |
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