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| Product Name | JTE 013 |
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| Description | Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. At concentrations up to 10 μM, displays 4.2% inhibition of S1P3 and does not antagonize S1P1. Enhances S1P-induced angiogenesis in vivo. Purity 98%. MW (observed): 408.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide |
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| Gene, Accession, CAS # | CAS: 383150-41-2 |
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| Catalog # | 2392/10 |
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| Price | |
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| Order / More Info | JTE 013 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 18426913, 18922980, 19157443, 19700468, 20435688, 20729401, 20837468, 21642988, 23300082, 23666803, 23732709, 24098536, 24293320, 25275309, 25621765, 26030100, 26748478, 26884643, 27402344, 30543684 |
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