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| Product Name | JTE 607 dihydrochloride |
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| Description | Cytokine release inhibitor. Inhibits production of IL-1β, IL-8, IL-6, IL-10 and TNFα (IC50 values are 5.9, 7.3, 8.8, 9.1 and 11.0 nM, respectively) from LPS-stimulated PBMCs. Reduces proinflammatory cytokine-release and attenuates lung permeability in a rat lung injury model. Induces apoptosis in leukemia cells in vitro and prolongs survival in a mouse leukemia model. Purity 98%. MW (observed): 597.36 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride |
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| Gene, Accession, CAS # | CAS: 188791-09-5 |
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| Catalog # | 5185/10 |
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| Order / More Info | JTE 607 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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