| 产品详情 |
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| Antigenic Specificity | Cyclophilin B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor 488 conjugate |
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| Size | 50 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclophilin B Polyclonal Antibody, Alexa Fluor 488. Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP). Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation. Thus, providing a possible mechanism of immunosuppression by CsA and FK506. Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective |
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| Immunogen | n/a |
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| Other Names | AI844835, SCYLP, Cphn-2, CypB, OI9, Scylp, Cphn2, AA553318, CyP-20b, CYPB, CYP-S1, AA408962 |
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| Gene, Accession # | Entrez: 19035, 478337, 5479, 64367; Uniprot: P23284, P24368, P24369 |
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| Catalog # | PA1-027A-A488 |
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| Price | |
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| Order / More Info | Cyclophilin B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23001183 |
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