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| Product Name | GRK5, Active |
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| Description | G protein-coupled receptor kinases (GRKs) play an important role in phosphorylating and regulating the activity of a variety of G protein-coupled receptors. Haribabu and Snyderman (1) identified GRK5 and GRK6. GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Bullrich (2) used a rodent-human hybrid panel to map 2 newly identified members of the GRK family: GPRK5 and GPRK6 to 10q24-qter and 5q35, respectively. Desensitization of G protein-coupl |
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| Size | 5 µg |
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| Concentration | 5µg/50 µl |
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| Applications | RUO |
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| Other Names | GRK, G protein-coupled receptor kinase 5 |
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| Gene, Accession, CAS # | GRK5, Gene ID: 2869, Accession: P34947 |
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| Catalog # | 7709-5 |
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| Order / More Info | GRK5, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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