| 产品详情 |
| Edit |   |
|---|
| Product Name | Ko 143 |
|---|
| Description | Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Inhibits ABCB1 and ABCC1 at higher concentrations. Rapidly metabolized in rat plasma. Purity 99%. MW (observed): 469.57 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester |
|---|
| Gene, Accession, CAS # | CAS: 461054-93-3 |
|---|
| Catalog # | 3241/10 |
|---|
| Price | |
|---|
| Order / More Info | Ko 143 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 21767647, 22200378, 23028879, 23063411, 23095522, 23822179, 24993496, 25691630, 25928015, 26199091, 26853103, 26983466 |
|---|
| 产品资料 |
|
|