| 产品详情 |
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| Antigenic Specificity | CENPO |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CENPO Polyclonal Antibody. Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patient |
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| Immunogen | n/a |
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| Other Names | CENP-O, ICEN-36, MCM21R; centromeric protein O; interphase centromere complex protein 36 |
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| Gene, Accession # | Entrez: 52504, 684439, 79172; Uniprot: Q8K015, Q9BU64 |
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| Catalog # | PA5-20826 |
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| Price | |
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| Order / More Info | CENPO Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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