| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | BRAP |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunoprecipitation: 2-5 µg/mg lysate |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | BRAP Polyclonal Antibody. Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. |
|---|
| Immunogen | n/a |
|---|
| Other Names | BRAP2, IMP, RNF52, BRCA1-associated protein, RING finger protein 52, galectin-2-binding protein, impedes mitogenic signal propagation, renal carcinoma antigen NY-REN-63 |
|---|
| Gene, Accession # | Entrez: 8315; Uniprot: Q7Z569 |
|---|
| Catalog # | A302-681A |
|---|
| Price | |
|---|
| Order / More Info | BRAP Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|