| 产品详情 |
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| Product Name | Bardoxolone |
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| Description | Bardoxolone is a synthetic oleanane triterpenoid that inhibits cellular iNOS production when stimulated by IFNg, TNF-α and IL-1. It is Reata's investigational lead molecule for CKD (chronic kidney disease). It is a potent inducer of the transcription factor Nrf2 which is an important biological target that controls the production of many of the body's antioxidant and detoxification enzymes. MW: 491.66. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid; RTA 402; CDDO |
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| Gene, Accession, CAS # | CAS: 218600-44-3 |
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| Catalog # | B1170-5 |
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| Order / More Info | Bardoxolone from BIOVISION, INC. |
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| Product Specific References | n/a |
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