| 产品详情 |
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| Product Name | Active Porcine Calpain 1 |
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| Description | The activity of Calpain activity is attributed to two main isoforms: n-calpain and m-calpain, which are ubiquitously, expressed proteases implicated in cellular migration, cell cycle progression, degenerative processes and cell death. These heterodimeric enzymes are composed of distinct catalytic subunits, encoded by Capn1 (n-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. CAPN1 is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of the substrates involved in cytoskeletal remodeling and signal transduction. CAPN1 is activated by micromolar concentrations of calcium and inhibited by calpastatin. MW: 110 kDa. Purity ≥85% |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Calpain-1 catalytic subunit, Calcium-activated neutral proteinase 1, CANP 1, Calpain mu-type, Calpain-1 large subunit, Micromolar-calpain |
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| Gene, Accession, CAS # | CAPN1, Gene ID: 397027, Accession: P35750 |
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| Catalog # | 1138-100 |
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| Price | |
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| Order / More Info | Active Porcine Calpain 1 from BIOVISION, INC. |
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| Product Specific References | n/a |
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