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Product Name | PEDF, human recombinant |
Description | PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature re |
Size | 100 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35 |
Gene, Accession, CAS # | PEDF, Gene ID: 5176, Accession: P36955 |
Catalog # | 4988-100 |
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Order / More Info | PEDF, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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