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| Product Name | Ataxin 3, 1-370aa, Human, E Coli |
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| Description | MW: 42.4 kDa (370aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. Ataxin 3 is also known as Machado-Joseph disease protein 1. Machado-Joseph disease is one of several hereditary autosomal dominant neurodegenerative disorders. This protein contains trinucleotide CAG repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. Ataxin 3 interacts with the major histone acetyltransferases cAMP-response-element binding pr |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Ataxin 3; ATX3; MJD; MJD1; SCA3; ATXN3; JOS; ATXN3; AT3; EC 3.4.22.; Josephin; Machado Joseph disease; Machado Joseph disease protein 1; Machado-Joseph disease protein 1 homolog; MJD gene; Rsca3; SCA3 gene; Spinocerebellar ataxia type 3 protein,] |
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| Gene, Accession, CAS # | ATXN3; ATXN3; AT3; JOS; MJD; ATX3; MJD1; SCA3; ATX3; MJD; MJD1; SCA3, Gene ID: 4287, Accession: AAH33711 |
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| Catalog # | MBS203345 |
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| Order / More Info | Ataxin 3, 1-370aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Doss Pepe EW., et al. (2003). Mol Cell Biol. 23 (18):6469-83. ; Paulson., et al. (1997). Ann Neurol. 41 (4):453-62.; |
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