| 产品详情 |
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| Antigenic Specificity | HP1 alpha |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, human, mouse, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 2-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HP1 alpha Polyclonal Antibody. CBX5, also known as Chromobox protein homolog 5, is a regulatory protein belonging to the Polycomb group proteins family with two chromo domains. CBX5 associates with chromosomes during mitosis, specifically with chromatin during metaphase and anaphase. A component of the centromeric and pericentromeric heterochromatin, CBX5 may interact with lamin B receptor (LBR) to contribute to the association of the heterochromatin with the inner nuclear membrane. CBX5 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. This methyl-lysine binding protein localized at heterochromatin sites is also known to mediate gene silencing and is involved in the formation of functional kinet |
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| Immunogen | n/a |
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| Other Names | HP1, HP1A, HP1 alpha homolog, HP1-ALPHA, HP1Hs alpha, antigen p25, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha |
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| Gene, Accession # | Entrez: 12419, 23468, 477593; Uniprot: P45973, Q61686 |
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| Catalog # | PA5-23357 |
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| Price | |
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| Order / More Info | HP1 alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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