| 产品详情 |
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| Antigenic Specificity | HP1 alpha |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:500, Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HP1 alpha Polyclonal Antibody. Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing. It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure. High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain. Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3. In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mou |
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| Immunogen | n/a |
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| Other Names | HP-1 alpha antibody, Antigen p25 antibody, Cbx5 antibody, Chromobox homolog 5 (HP1 alpha homolog Drosophila) antibody, Chromobox protein homolog 5 ant |
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| Gene, Accession # | Entrez: 23468; Uniprot: P45973 |
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| Catalog # | PA1-16942 |
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| Price | |
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| Order / More Info | HP1 alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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