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Product Name | Recombinant Human NP-1 Protein |
Description | Defensins (α and β) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the β-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Neutrophil defensin 1;Defensin, alpha 1;HNP-1;HP-1;HP1;HP 1-56;Neutrophil defensin 2;HNP-2;HP-2;HP2;DEFA1;DEF1, DEFA2, MRS;DEFA1B; Neutrophil Peptide-1, alpha Defensin-1, HNP-1, Cryptdin |
Gene, Accession, CAS # | DEFA1, UniProt: P59665 |
Catalog # | PROTP59665 |
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Order / More Info | Recombinant Human NP-1 Protein from BOSTER BIO |
Product Specific References | n/a |
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