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| Product Name | TC-E 5008 |
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| Description | Selective mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor (Ki = 120-190 nM). Displays >60-fold selectivity for mIDH1 (found in ~75% of gliomas) over wild type IDH1. Also inhibits D-2-hydroxyglutaric acid in cells expressing mIDH1 (EC50 = 2.4 μM). Does not display cytotoxicity towards non-cancerous human cells. Phenotypically lethal. MW (observed): 215.25. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone. SYC 435 |
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| Gene, Accession, CAS # | CAS: 50405-58-8 |
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| Catalog # | 5244/10 |
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| Price | |
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| Order / More Info | TC-E 5008 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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