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Product Name | NCX 4040 |
Description | NO-donating aspirin; anti-inflammatory. Blocks inflammatory mediator production in isolated human monocytes (IC50 values are 0.07, 0.13, 0.15 and 0.18 μM for IL-1β, PGE2, IL-10 and TNF-α respectively). Decreases COX-2 expression (IC50 = 0.13 μM); disrupts proteasome-mediated degradation of iκB-α. Antiproliferative in HCT116 colon cancer cells; sensitizes drug-resistant ovarian tumor cells to cisplatin (Cat. No. 2251). Purity 98%. MW (observed): 331.28 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester |
Gene, Accession, CAS # | CAS: 287118-97-2 |
Catalog # | 4531/50 |
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Order / More Info | NCX 4040 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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