| 产品详情 |
| Edit |   |
|---|
| Product Name | NDT 9513727 |
|---|
| Description | Potent C5a receptor (C5aR) negative allosteric modulator (NAM) (IC50 = 11.6 nM); selective for human C5aR (IC50 values for rat and mouse C5aR are > 10 μM). Exhibits inverse agonist pharmacokinetics. Blocks degranulation response in C5a-stimulated U937 cells (IC50 = 7.1 nM). Exhibits selectivity for primate and gerbil receptor over other species. Orally bioavailable. Purity 98%. MW (observed): 573.68 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N,N-Bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-Imidazole-5-methanamine |
|---|
| Gene, Accession, CAS # | CAS: 439571-48-9 |
|---|
| Catalog # | 3333/50 |
|---|
| Price | |
|---|
| Order / More Info | NDT 9513727 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 29867214 |
|---|
| 产品资料 |
|
|