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| Product Name | NDT 9513727 |
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| Description | Potent C5a receptor (C5aR) negative allosteric modulator (NAM) (IC50 = 11.6 nM); selective for human C5aR (IC50 values for rat and mouse C5aR are > 10 μM). Exhibits inverse agonist pharmacokinetics. Blocks degranulation response in C5a-stimulated U937 cells (IC50 = 7.1 nM). Exhibits selectivity for primate and gerbil receptor over other species. Orally bioavailable. Purity 98%. MW (observed): 573.68 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N-Bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-Imidazole-5-methanamine |
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| Gene, Accession, CAS # | CAS: 439571-48-9 |
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| Catalog # | 3333/10 |
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| Price | |
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| Order / More Info | NDT 9513727 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 29867214 |
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| 产品资料 |
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