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| Product Name | Necrostatin-1 |
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| Description | ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM). Blocks non-apoptotic cell death via inhibition of a specific cellular pathway, necroptosis, which leads to necrosis (EC50 = 494 nM). Reduces ischemic brain injury in a mouse model of stroke. Purity 99%. MW (observed): 259.33 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone |
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| Gene, Accession, CAS # | CAS: 4311-88-0 |
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| Catalog # | 2324/10 |
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| Price | |
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| Order / More Info | Necrostatin-1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25324692, 28569199 |
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