| 产品详情 |
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| Product Name | API-1 |
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| Description | Akt/protein kinase B (PKB) inhibitor. Binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation. Inhibits EGF-induced kinase activity of Akt1, Akt2 and Akt3. Induces cell growth arrest and apoptosis in human cancer cells expressing constitutively active Akt. Displays antitumor activity in vitro and in vivo. Purity 96%. MW (observed): 337.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide |
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| Gene, Accession, CAS # | CAS: 36707-00-3 |
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| Catalog # | 3897/10 |
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| Price | |
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| Order / More Info | API-1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22463935, 27659207 |
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| 产品资料 |
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