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| Product Name | Apoptosis Activator 2 |
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| Description | Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM). Purity 99%. MW (observed): 306.14 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
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| Gene, Accession, CAS # | CAS: 79183-19-0 |
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| Catalog # | 2098/10 |
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| Price | |
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| Order / More Info | Apoptosis Activator 2 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 16172114, 26768768 |
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| 产品资料 |
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