| 产品详情 |
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| Product Name | BIBU 1361 dihydrochloride |
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| Description | Potent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM). Displays ~ 100-fold lower potency against ErbB2 (IC50 = 290 nM) and is selective over a range of other related tyrosine kinases (IC50 > 10 μM). Blocks downstream EGFR signaling events such as MAPKK/MAPK activation. Oral administration inhibits growth of established human xenografts in athymic mice. Purity 97%. MW (observed): 516.87 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-amine dihydrochloride |
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| Gene, Accession, CAS # | CAS: 793726-84-8 |
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| Catalog # | 2417/1 |
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| Price | |
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| Order / More Info | BIBU 1361 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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