产品详情 |
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Product Name | BIBX 1382 dihydrochloride |
Description | Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM). Displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). Oral administration inhibits growth of established human xenografts in athymic mice. Purity 97%. MW (observed): 460.77 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)-pyrimido[5,4-d]pyrimidine-2,8-diamine dihydrochloride |
Gene, Accession, CAS # | CAS: 1216920-18-1 |
Catalog # | 2416/10 |
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Order / More Info | BIBX 1382 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 23792643 |
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