产品详情 |
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Product Name | BIRB 796 |
Description | High affinity and selective p38 kinase inhibitor (Kd = 50-100 pM). Exhibits no significant inhibition on a panel of related kinases. Inhibits LPS-induced TNFα production in human PBMCs and whole blood (IC50 values are 21 and 960 nM, respectively). Also inhibits JNK2α2 and c-Raf-1 (IC50 values are 98 nM and 1.4 μM, respectively). Cell permeable. Purity 99%. MW (observed): 527.66 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea. Doramapimod |
Gene, Accession, CAS # | CAS: 285983-48-4 |
Catalog # | 5989/50 |
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Order / More Info | BIRB 796 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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