| 产品详情 |
| Edit |   |
|---|
| Product Name | BIRT 377 |
|---|
| Description | Potent negative allosteric modulator of LFA-1 (lymphocyte function-associated antigen-1) (Kd = 26 nM). Binds to the I-domain of LFA-1. Reversibly inhibits LFA-1 mediated binding of SKW3 leukemia cells to ICAM-1. Inhibits superantigen (SEB)-induced IL-2 production from lymphocytes in vitro and attenuates the SEB-induced increase in IL-2 plasma levels in a mouse model in vivo. Orally available. Purity 98%. MW (observed): 442.13 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (5R)-5-[(4-Bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione |
|---|
| Gene, Accession, CAS # | CAS: 213211-10-0 |
|---|
| Catalog # | 4776/50 |
|---|
| Price | |
|---|
| Order / More Info | BIRT 377 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|