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| Product Name | 6,8-Bis(benzylthio)octanoic acid |
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| Description | Pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase (KGDH) inhibitor. Disrupts tumor cell mitochondrial metabolism, and increases mitochondrial reactive oxygen species (ROS) production in H460 lung carcinoma cells. Has no effect on KGDH activity in normal bronchial epithelial cells. Induces cell death of multiple tumor cell lines selectively over normal cells in vitro. Inhibits tumor growth of H460 and BxPC-3 tumor cell xenografts in mice. Purity 99%. MW (observed): 388.59 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6,8-Bis[(phenylmethyl)thio]octanoic acid |
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| Gene, Accession, CAS # | CAS: 95809-78-2 |
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| Catalog # | 5348/50 |
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| Order / More Info | 6,8-Bis(benzylthio)octanoic acid from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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