| 产品详情 |
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| Product Name | Bisindolylmaleimide II |
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| Description | Potent, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 0.01 μM). Displays selectivity for PKC over protein kinase A (PKA) and phosphorylase kinase (PK) (IC50 values are 0.75 and 2μM for PK and PKA respectively). Also displays potent, noncompetitive antagonism at nicotinic cholinergic receptors (IC50 ~ 0.03 μM for inhibition of catecholamine secretion in nicotine-stimulated PC-12 cells). Purity 97%. MW (observed): 438.52 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione |
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| Gene, Accession, CAS # | CAS: 137592-45-1 |
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| Catalog # | 4128/50 |
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| Order / More Info | Bisindolylmaleimide II from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 15269224 |
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| 产品资料 |
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