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| Product Name | SB 203580 hydrochloride |
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| Description | Water-soluble salt of SB 203580 (Cat. No. 1202). Selective inhibitor of p38 mitogen-activated protein kinase (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα. Shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. Purity 98%. MW (observed): 413.89 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride |
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| Gene, Accession, CAS # | CAS: 869185-85-3 |
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| Catalog # | 1402/10 |
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| Order / More Info | SB 203580 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 15852038, 17032753, 22915755, 24732880, 25143547, 26271343 |
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